Tags: Colloquium Series

The Statistics Department hosts weekly colloquia on a variety of statistcal subjects, bringing in speakers from around the world.


Rui Song

Dynamic treatment regimen is emerging as a new strategy for treatment which takes individual heterogeneity in disease severities, background characteristics and related clinical measurements into consideration. In this work, we propose a strategy to select variables with qualitative interactions to get the optimal treatment regime based on sequential advantage. We will demonstrate the proposed method with extensive numerical results and a real…


Jin Tang

Semiparametric regression models have been wildly applied into the longitudinal data. In this dissertation, we model generalized longitudinal data from multiple treatment groups by a class of semiparametric analysis of covariance models, which take into account the parametric effects of time dependent covariates and the nonparametric time effects. In these models, the treatment effects are represented by nonparametric functions of time and we…


Yijuan Hu

In the large cohorts typically used for genome-wide association studies (GWAS), it is not economically feasible to sequence all cohort members. A cost-effective strategy is to sequence subjects with extreme values of quantitative traits or those with specific diseases. By imputing the sequencing data from the GWAS data for the cohort members who are not selected for sequencing, one can dramatically increase the number of subjects with…


Zhou Yu

We propose trace pursuit for model-free variable selection under the sufficient dimension reduction paradigm. Two distinct algorithms are proposed: stepwise trace pursuit and forward trace pursuit, both of which can be combined with many existing sufficient dimension reduction methods. Stepwise trace pursuit achieves selection consistency with fixed dimension p, and is readily applicable in the challenging p>n setting. Forward trace pursuit…


Min Yang

The usefulness and popularity of nonlinear models have spurred a large literature on data analysis, but research on design selection has not kept pace. One complication in studying optimal designs for nonlinear models is that information matrices and optimal designs depend on unknown parameters. Besides the popular locally optimal designs strategy, another common approach is to use Bayesian optimal design approach, which typically means an…


Jason Kao

Functional magnetic resonance imaging (fMRI) is one of the leading brain mapping technologies for studying brain activity in response to mental stimuli. For neuroimaging studies utilizing this pioneering technology, there is a great demand of high-quality experimental designs that help to collect informative data to make precise and valid inference about brain functions. In this talk, I provide a survey on some recently developed analytical and…


Joyee Ghosh

In this talk we will give a quick overview of some of the strengths and challenges in Bayesian variable selection as it evolved over the last two decades. We will then discuss two specific problems in linear regression with strong multicollinearity among the covariates. A variety of Markov chain Monte Carlo algorithms  have been proposed in the literature for Bayesian variable selection in linear regression. The computation for these…


Hsin-Ping Wu

Finding optimal designs for generalized linear models is a challenging problem. Recent research has identified the structure of optimal designs for generalized linear models with a single or multiple independent explanatory variables that appear as first-order terms in the predictor. We consider generalized linear models with a single-variable quadratic polynomial predictor under a popular family of optimality criteria. When the design region is…


Snehalata Huzurbazar

Gene duplication is the key mechanism for evolutionary change. To infer the timing and nature of gene duplication, the 'data' used are the end result of various pipelines. In this talk, I will summarize how the 'data' are obtained, explore the shortcomings of analyses in the literature, and end with current work on overcoming these shortcomings. The interesting statistical problems are that the 'data' are maximum likelihood estimates, and that…


C.F. Jeff Wu

Dr. Wu will speak at this year's Bradley Lecture on Friday April 25, 2014 at 4:30pm.  An RSVP is required to attend this lecture. Young (and some not-so-young) researchers often wonder how to extract good research ideas and develop useful methodologies from solving real world problems. The path is rarely straightforward and its success depends on the circumstances, tenacity and luck. I will use three examples to illustrate how I trod the…
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