Tags: Colloquium Series

The Statistics Department hosts weekly colloquia on a variety of statistcal subjects, bringing in speakers from around the world.


Weng Kee Wong

Experimental costs are rising and it is important to use minimal resources to make statistical inference with maximal precision. Optimal design theory and ideas are increasingly applied to address design issues in a growing number of disciplines, and they include biomedicine, biochemistry, education, agronomy, manufacturing industry, toxicology and food science, to name a few.   I first present a brief overview of optimal design…


Jiming Jiang

We study behavior of the restricted maximum likelihood (REML) estimator under a misspecified linear mixed model (LMM) that has received much attention in recent gnome-wide association studies. The asymptotic analysis establishes consistency of the REML estimator of the variance of the errors in the LMM, and convergence in probability of the REML estimator of the variance of the random effects in the LMM to a certain limit, which is equal to the…


Lynne Billard

Massively large data sets are routine and ubiquitous given modern computer capabilities. What is not so routine is how to analyse these data. One approach is to aggregate the data sets according to some scientific criteria. The resultant data are perforce symbolic data, i.e., lists, intervals, histograms, and so on. Applications abound, especially in the medical and social sciences. Other data sets (small or large in size) are naturally symbolic…


Christopher Nachtsheim

Definitive Screening Designs (DSDs), discovered in 2011, are a new alternative to standard two-level screening designs. There are many desirable features of this family of designs. They require few runs while providing orthogonal main effects and avoiding any confounding of main effects by two-factor interactions. In addition they allow for estimating any quadratic effect of the continuous factors. The two-factor interactions are correlated but…


Pengsheng Ji

We collect the coauthor and citation data for all research papers published in four of the top journals in statistics between 2003 and 2012, analyze the data from several different perspectives (e.g., patterns, trends, community structures) and present an array of interesting findings. (1) Both the average numbers of papers per author published in these journals and the fraction of self citations have been decreasing, but the proportion of…


Dennis Lin

Dimensional Analysis (DA) is a fundamental method in the engineering and physical sciences for analytically reducing the number of experimental variables prior to the experimentation.  The principle use of dimensional analysis is to reduce from a study of the dimensions of the variables on the form of any possible relationship between those variables.  The method is of great generality.  In this talk, an overview/introduction of…


Hokwon Cho

We propose sequential methods for obtaining approximate confidence limits and optimal sample sizes for the risk ratio (RR) of two independent binomial variates and a measure of reduction (MOR). The procedure is developed based on a modified maximum likelihood estimator (MLE) for the ratio. First-order asymptotic expansions are obtained for large-sample properties of the proposed procedure and we investigate its finite sample behavior through…


Sujit Ghosh

Data processing and source identification using lower dimensional hidden structure plays an essential role in many fields of applications, including image processing, neural networks, genome studies, signal processing and other areas where large datasets are often encountered. Representations of higher dimensional random vector using a lower dimensional vector provide a statistical framework to the identification and separation of the sources.…


Bradley Jones

Latin Hypercube designs (LHD) are in standard use as plans for deterministic computer experiments. However, these designs depend on the ability of the investigator to set each factor independently of all the others. To be specific, the implied design region for an LHD is a square, cube or hypercube. However, there are cases where some parts of such a design region may be inaccessible or even nonsensical. In such cases it is useful to be able to…


Feifang Hu

Advances in genetics have allowed scientists to identify genes (biomarkers) that are linked with certain diseases. To translate these great scientific findings into real-world products (personalized medicine) for those who need them, clinical trials play an essential and important role. To develop personalized medicine, we need new designs of clinical trials so that genetics information and other biomarkers can be incorporated in treatment…
Subscribe to Colloquium Series