M. Reza Meshkani

Shahid Beheshti University

Analysis of Covariance under Inverse Gaussian Model

In this talk, the limitations of normal model for Analysis of Covariance for positive right-skewed variables are considered. Specifically, an Inverse Gaussian variable is considered whose variance depends on its mean thus violating the usual assumptions of Normal linear model. Instead of appealing to transformations which makes interpretations of the results awkward, we propose a method of direct statistical analysis from both Maximum Likelihood and Bayesian perspectives. The formulas for adjusting treatment effects are given and their properties are discussed.

Tuesday, April 17, 2012 - 3:30pm

Antony Joseph

Yale University

Near-optimal recovery using iterative algorithms in high-dimensional regression with random designs

We provide theoretical analysis of iterative algorithms for two problems in high-dimensional regression. In the first, a sparse linear model with a specific coefficient structure provides a framework for a problem in communication. We show that the algorithm has optimal performance when compared to information-theoretic limits. This provides theoretically provable, low computational complexity communication systems based on our statistical framework.

Thursday, February 2, 2012 - 3:30pm

Pengsheng Ji

Cornell University

UPS Delivers Optimal Phase Diagram in High Dimensional Variable Selection

Consider a linear model Y = X + z, z N(0; In). Here, X = Xn;p, where both p and n are large, but p > n. We model the rows of X as i.i.d. samples from N(0; 1 n ), where is a pp correlation matrix, which is unknown to us but is presumably sparse. The vector is also unknown but has relatively few nonzero coordinates, and we are interested in identifying these nonzeros. We propose the Univariate Penalization Screeing (UPS) for variable selection. This is a screen and clean method where we screen with univariate thresholding, and clean with penalized MLE.

Thursday, January 26, 2012 - 3:30pm

Kehui Chen

University of California, Davis

Modeling Conditional Distributions for Functional Data and Stringing High-Dimensional Data to Functions

In this talk, I will first present a method for conditional distribution and quantile estimation when predictors take values in a functional space, which is an extension of the usual functional mean regression. The study is motivated and illustrated by an application to the assessment of children’s growth patterns. The proposed method is supported by theory and is shown to perform well in simulations. An extension of the proposed conditional approach to model the more complex case when responses are also functions will be briefly discussed.

Tuesday, January 24, 2012 - 3:30pm

Roger Woodard

A Large Course Redesign of Introductory Statistics: You don't need 65 other people with you to learn a definition.

Statistics 311 at NCSU is a large introductory course that serves over 700 students per semester. In this talk I will present the results of a redesign that transformed this course in a hybrid format. This project converted two of the three hours of student contact to an online format. Students still come together one day a week to participate in discussions where an instructor teaches them the important ideas and concepts. During this time students also participate in group activities that illustrate key ideas.

Thursday, January 19, 2012 - 3:30pm

Luyan Dai

Boehringer Ingelheim Pharmaceuticals, Inc.

Empirical Bayesian Methods for Enrollment and Event Projection in Oncology Trials

In oncology trials with time to event as primary endpoints, the trial duration is mainly driven by the number of events observed to ensure sufficient power to draw confirmatory conclusions. The trial planning determined by clinical staff and the deterministic techniques fails to account for the uncertainties and stochastic fluctuations in the recruitment process and event evolvement. In this project, we incorporate a Poisson-gamma recruitment process into an exponential event prediction model under the empirical Bayesian setting.

Thursday, January 12, 2012 - 3:30pm

Warren Kuhfeld

SAS Institute

Recent Directions in SAS Statistical and Graphical Software

This presentation begins with a behind-the-scenes look at how research statistician developers at SAS interact with customers and the statistical community to decide on new functionality in SAS/STAT. The presentation then provides a high-level tour of new directions and features in the most recent releases of SAS/STAT (9.2, 9.22, and 9.3).

Friday, October 21, 2011 - 9:00am

Hanxiang Peng

On Maximum Empirical Likelihood Estimation And Related Topics

In this talk, we present maximum empirical likelihood estimation in the case of constraint functions that may be discontinuous and/or depend on additional parameters. The key to our analysis is a uniform local asymptotic normality condition for the local empirical likelihood ratio. This condition holds under mild assumptions and allows for a study of maximum empirical likelihood estimation and empirical likelihood ratio testing similar to that for parametric models.

Thursday, September 1, 2011 - 3:30pm

Yan Daniel Zhao

University of Oklahoma Health Sciences Center at Tulsa

Design and Analysis Considerations in Clinical Trials With a Sensitive Subpopulation

We present research on clinical trials with a sensitive subpopulation of patients, that is, a subgroup that is more likely to benefit from the treatment than the overall population. Given a sensitive subgroup defined by a prespecified classifier, for example, a clinical marker or pharmacogenomic marker, the trial’s outcome is declared positive if the treatment effect is established in the overall population or in the subgroup.

Thursday, December 1, 2011 - 3:30pm


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