TitleGeneralized Functional Linear Models With Semiparametric Single-Index Interactions
Publication TypeJournal Article
Year of Publication2010
AuthorsLi, Y, Wang, N, Carroll, RJ
JournalJOURNAL OF THE AMERICAN STATISTICAL ASSOCIATION
Volume105
Pagination621-633
Date PublishedJUN
ISSN0162-1459
Abstract

We introduce a new class of functional generalized linear models, where the response is a scalar and some of the covariates are functional. We assume that the response depends on multiple covariates, a finite number of latent features in the functional predictor, and interaction between the two. To achieve parsimony, the interaction between the multiple covariates and the functional predictor is modeled semipara-metrically with a single-index structure. We propose a two-step estimation procedure based on local estimating equations, and investigate two situations: (a) when the basis functions are predetermined, e.g.. Fourier or wavelet basis functions and the functional features of interest are known: and (b) when the basis functions are data driven, such as with functional principal components. Asymptotic properties are developed. Notably, we show that when the functional features are data driven, the parameter estimates have an increased asymptotic variance due to the estimation error of the basis functions. Our methods are illustrated with a simulation study and applied to an empirical dataset where a previously unknown interaction is detected. Technical proofs of our theoretical results are provided in the online supplemental materials.

DOI10.1198/jasa.2010.tm09313
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